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Table 2 The pathogenicity of NDV JSD0812 strain in Gaoyou ducks of different ages

From: Experimental infection of duck origin virulent Newcastle disease virus strain in ducks

Age (days)

Inoculation route1

Inoculation dose

Morbidity (%) (no. diseased/no. inoculated)

Mortality (%) (no. died/no. inoculated)

Mean serum HI titer2

15

IM

5 × 108 ELD50

100 (10/10)

60 (6/10)

5.40 ± 0.84

IN & IO

5 × 108 ELD50

100 (10/10)

0 (0/10)

5.25 ± 0.96

30

IM

5 × 108 ELD50

100 (10/10)

40 (4/10)

7.17 ± 0.75

IN & IO

5 × 108 ELD50

100 (10/10)

0 (0/10)

5.30 ± 0.95

45

IM

5 × 108 ELD50

100 (10/10)

10 (1/10)

6.22 ± 0.97

IN & IO

5 × 108 ELD50

50 (5/10)

0 (0/10)

6.11 ± 1.05

60

IM

5 × 108 ELD50

100 (10/10)

10 (1/10)

5.90 ± 0.74

IN & IO

5 × 108 ELD50

30 (3/10)

0 (0/10)

5.22 ± 1.20

110

IM

5 × 108 ELD50

100 (10/10)

0 (0/10)

7.00 ± 1.22

IN & IO

5 × 108 ELD50

40 (4/10)

10 (1/10)

5.40 ± 1.26

  1. 1IM: inoculated intramuscularly; IN & IO: inoculated intranasally and intraocularly.
  2. 2Antibody detection was performed on day 15 PI and JSD0812 strain was used as antigen in HI tests. Values represent the mean ± SD and were expressed as log2 exponents.