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Table 3 Effect of metoclopramide on open-field activity and tonic immobility test in chicks

From: Metoclopramide-induced central nervous system depression in the chicken

Metoclopramide (mg/kg, subcutaneously)

Squares crossed/5 minutes

Duration of immobility (second)

0 (saline-control)

3.5 ± 1.4

10.5 ± 2.7

5

1.0 ± 1.0*

54.9 ± 18.1

10

0.1 ± 0.1*

130.6 ± 26.3*†

  1. Open-field activity was measured 20 min after drug administration. Tonic immobility test was done immediately after the open-field test.
  2. Values are mean ± SE of 8 chicks/group.
  3. * Significantly different from the respective control values, P < 0.05.
  4. † Significantly different from the 5 mg/kg treatment group, P < 0.05.
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BMC Veterinary Research

ISSN: 1746-6148

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